KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA2A
All Species:
0
Human Site:
S258
Identified Species:
0
UniProt:
P08913
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08913
NP_000672.3
450
48957
S258
N
G
L
G
P
E
R
S
A
G
P
G
G
A
E
Chimpanzee
Pan troglodytes
XP_521603
468
50335
E249
S
A
G
P
G
G
A
E
A
E
P
L
P
T
Q
Rhesus Macaque
Macaca mulatta
XP_001087738
450
49113
G258
N
G
L
G
P
E
R
G
A
G
P
G
G
A
E
Dog
Lupus familis
XP_544018
622
67080
R273
N
G
L
G
P
E
R
R
P
A
G
P
G
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q01338
450
48847
G258
N
G
L
G
P
E
R
G
A
G
P
T
G
A
E
Rat
Rattus norvegicus
P22909
450
48921
G258
N
G
L
G
P
E
R
G
A
G
T
A
G
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513049
394
43582
N236
I
H
V
A
N
F
F
N
L
F
I
I
I
T
W
Chicken
Gallus gallus
XP_426355
614
69002
R432
A
G
G
C
T
S
L
R
M
Q
L
G
E
N
G
Frog
Xenopus laevis
P24628
442
49720
V248
V
K
L
C
S
V
F
V
K
S
N
G
S
F
P
Zebra Danio
Brachydanio rerio
Q90WY4
388
43978
K230
K
E
N
D
P
H
E
K
L
N
G
I
Q
N
A
Tiger Blowfish
Takifugu rubipres
P53453
463
52101
E252
K
D
K
C
T
H
P
E
D
V
R
L
C
T
M
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200819
471
53401
G275
D
D
R
T
N
F
D
G
K
T
Y
A
M
I
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
96.4
58.5
N.A.
92.2
90.8
N.A.
45.5
43
33.3
60.4
32.6
N.A.
N.A.
N.A.
36
Protein Similarity:
100
86.1
96.6
62
N.A.
94
92.8
N.A.
53.1
51.2
50.6
70.6
49.4
N.A.
N.A.
N.A.
53
P-Site Identity:
100
13.3
93.3
53.3
N.A.
86.6
80
N.A.
0
13.3
13.3
6.6
0
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
93.3
53.3
N.A.
86.6
80
N.A.
13.3
13.3
13.3
6.6
0
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
0
0
9
0
42
9
0
17
0
34
17
% A
% Cys:
0
0
0
25
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
9
17
0
9
0
0
9
0
9
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
42
9
17
0
9
0
0
9
0
34
% E
% Phe:
0
0
0
0
0
17
17
0
0
9
0
0
0
9
0
% F
% Gly:
0
50
17
42
9
9
0
34
0
34
17
34
42
9
9
% G
% His:
0
9
0
0
0
17
0
0
0
0
0
0
0
0
9
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
9
17
9
9
0
% I
% Lys:
17
9
9
0
0
0
0
9
17
0
0
0
0
0
0
% K
% Leu:
0
0
50
0
0
0
9
0
17
0
9
17
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
9
% M
% Asn:
42
0
9
0
17
0
0
9
0
9
9
0
0
17
0
% N
% Pro:
0
0
0
9
50
0
9
0
9
0
34
9
9
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
9
% Q
% Arg:
0
0
9
0
0
0
42
17
0
0
9
0
0
0
0
% R
% Ser:
9
0
0
0
9
9
0
9
0
9
0
0
9
0
0
% S
% Thr:
0
0
0
9
17
0
0
0
0
9
9
9
0
25
0
% T
% Val:
9
0
9
0
0
9
0
9
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _